Open Access<p>The Long Non-Coding RNA <em>IDH1-AS1</em> Promotes Prostate Cancer Progression by Enhancing IDH1 Enzyme Activity</p>
Author(s) -
Shuo Wu,
Liang Ding,
HaiBing Xu,
Jie Gao,
Yunpeng Shao,
Sicong Zhang,
Zuoan Wei
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s251915
Subject(s) - idh1 , gene knockdown , isocitrate dehydrogenase , prostate cancer , cancer research , western blot , biology , cancer , prostate , enzyme , gene , biochemistry , genetics , mutation
Long non-coding RNAs (lncRNAs) are involved in the development of various tumors including prostate cancer. The purpose of this study was to explore the function of a natural antisense RNA, IDH1-AS1 , exerting potential carcinogenic effects in prostate cancer through a novel molecular mechanism.