Open Access<p>TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling</p>
Author(s) -
Xiumei Zhang,
Yalan Luo,
Qingchang Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s250766
Subject(s) - wnt signaling pathway , breast cancer , cell cycle , cancer research , cell growth , gene knockdown , cell migration , cancer , western blot , biology , flow cytometry , cell , signal transduction , pathology , medicine , cell culture , microbiology and biotechnology , gene , biochemistry , genetics
Evidence describing TMED3 in the context of breast cancer is scarce, and the effect of TMED3 on Wnt/β-catenin signaling in breast cancer has not been reported. The objective of this study was to determine the potential physiological functions and molecular mechanisms of TMED3 in breast cancer.