Open Access<p>Down-Regulated CMTM2 Promotes Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma</p>
Author(s) -
Shidong Zhang,
Run Tian,
Chunhua Bei,
Huixia Zhang,
Juan Kong,
Chuanjun Zheng,
Xin Song,
Di Li,
Hongzhuan Tan,
Xiaonian Zhu,
Shengkui Tan
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s250370
Subject(s) - epithelial–mesenchymal transition , hepatocellular carcinoma , cancer research , metastasis , cell migration , cell growth , mesenchymal stem cell , cell , chemokine , chemistry , medicine , pathology , biology , cancer , receptor , biochemistry
Our recent study identified that human chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing family member 2 (CMTM2) was deregulated in hepatocellular carcinoma (HCC) tissues and posed as a potential tumor suppressor. However, the mechanism of CMTM2 in HCC occurrence and development has not been well elaborated.