Open Access<p>PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer</p>
Author(s) -
Yiqun Zhang,
Jiajia Li,
Xuhui Dong,
Dan Meng,
Xiuling Zhi,
Yuan Liu,
Liangqing Yao
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s250066
Subject(s) - epithelial ovarian cancer , ovarian cancer , medicine , balance (ability) , reduction (mathematics) , cancer research , oncology , chemistry , cancer , physical therapy , geometry , mathematics
A growing number of studies have found that the serine-glycine biosynthesis pathway is highly activated for biosynthesis in cancer progression and metastasis. Phosphoserine aminotransferase 1 (PSAT1) catalyzes the second step of the serine-glycine biosynthesis pathway; the effects and mechanism of PSAT1 in epithelial ovarian cancer (EOC) remains unclear.