Open Access<p>Case Report of Anti-CD123 Chimeric Antigen Receptor T-Cell Therapy Followed by Radiotherapy for a Recurrence of Blastic Plasmacytoid Dendritic Cell Neoplasm After Allogeneic Hematopoietic Stem Cell Transplantation</p>
Author(s) -
Yili Jiang,
Qing Li,
Ting Yuan,
Yanyu Jiang,
Qi Deng
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s250016
Subject(s) - interleukin 3 receptor , medicine , radiation therapy , transplantation , hematopoietic stem cell transplantation , chimeric antigen receptor , haematopoiesis , plasmacytoid dendritic cell , stem cell , myeloid , oncology , cancer research , immunology , immunotherapy , antigen , dendritic cell , cancer , biology , genetics
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic malignancy. There is no standard chemotherapy regimen for BPDCN, and even allogeneic hematopoietic stem cell transplantation (allo-HSCT) has not been able to extend the survival of patients with BPDCN.