Open Access<p>Novel lncRNA SFTA1P Promotes Tumor Growth by Down-Regulating miR-4766-5p via PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma</p>
Author(s) -
Guohong Huang,
Yimei Yang,
Mengxin Lv,
Tian Huang,
Xiaoyan Zhan,
Wei Kang,
Jianghou Hou
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s248660
Subject(s) - gene knockdown , pi3k/akt/mtor pathway , protein kinase b , apoptosis , cancer research , hepatocellular carcinoma , viability assay , cell growth , medicine , cell , chemistry , biochemistry
Hepatocellular carcinoma (HCC) is a common malignancy worldwide with a high mortality rate. lncRNA SFTA1P is highly expressed in HCC. We aimed to study the role of SFTA1P in HCC and its relationship with miR-4766-5p.