Open Access<p>WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling</p>
Author(s) -
Jingjing Dai,
Longfeng Jiang,
Lei Qiu,
YuYun Shao,
Ping Shi,
Jun Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s248570
Subject(s) - hepatocellular carcinoma , biology , cancer research , cell growth , gene knockdown , blot , downregulation and upregulation , immunohistochemistry , immunofluorescence , cell culture , signal transduction , microbiology and biotechnology , gene , immunology , biochemistry , genetics , antibody
Wolf-Hirschhorn syndrome candidate gene-1 (WHSC1) plays key regulatory roles in cancer development and progression. However, its specific functions and potential mechanisms of action remain to be described in hepatocellular carcinoma (HCC).