Open Access<p>STAT3-Induced Upregulation of lncRNA CASC9 Promotes the Progression of Bladder Cancer by Interacting with EZH2 and Affecting the Expression of PTEN</p>
Author(s) -
Bo Yuan,
Rong Sun,
Yuming Du,
Zhang Jia,
Wencheng Yao,
Jinjian Yang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s248006
Subject(s) - pten , chromatin immunoprecipitation , gene silencing , downregulation and upregulation , ezh2 , gene knockdown , tensin , cancer research , biology , microbiology and biotechnology , stat3 , pi3k/akt/mtor pathway , chemistry , cell culture , signal transduction , gene expression , promoter , gene , genetics
Long non-coding RNA (lncRNA) cancer susceptibility candidate 9 ( CASC9 ) has been reported to play a vital role in tumorigenesis. This study explored the biological role of CASC9 and its regulation mechanism in bladder cancer (BC).