Open Access<p>FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling</p>
Author(s) -
Menghua Xie,
Lin Cai,
Jingduo Li,
Jing Zhao,
Yingxue Guo,
Zaiyu Hou,
Xiupeng Zhang,
Hua Tian,
Ailin Li,
Yuan Miao
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s247491
Subject(s) - cyclin d1 , wnt signaling pathway , cancer research , cell cycle , cell growth , carcinogenesis , biology , immunohistochemistry , cyclin b1 , lung cancer , medicine , pathology , signal transduction , cancer , cyclin dependent kinase 1 , microbiology and biotechnology , genetics
FAM110B is a member of the FAM110 family (family with sequence similarity 110), which is a component of the centrosome associated proteins. Previous studies have shown that FAM110B may be involved in the process of cell cycle and may play a role in carcinogenesis and tumor progression. Using an online database, we found that FAM110B may predict favorable prognosis in non-small cell lung cancer (NSCLC). Therefore, the role of FAM110B playing in NSCLC needs to be further investigated.