Open Access<p>The microRNA miR-3174 Suppresses the Expression of ADAM15 and Inhibits the Proliferation of Patient-Derived Bladder Cancer Cells</p>
Author(s) -
Chunhu Yu,
Ying Wang,
Tiejun Liu,
Kefu Sha,
Zhaoxia Song,
Mingmin Zhao,
Xiaolin Wang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s246710
Subject(s) - microrna , bladder cancer , cancer research , cancer , cell growth , cancer cell , western blot , biology , medicine , gene , biochemistry
Bladder cancer is a major urinary system cancer, and its mechanism of action regarding its progression is unclear. The goal of this study was to examine the expression of ADAM panel in the clinical specimens of bladder cancer and to investigate the role of miR-3174/ADAM15 (a disintegrin and metalloprotease 15) axis in the regulation of bladder cancer cell proliferation.