Open Access<p>LncRNA TTN-AS1 Regulates miR-524-5p and RRM2 to Promote Breast Cancer Progression</p>
Author(s) -
Hui Feng,
Qi Wang,
Wenjing Xiao,
Biyuan Zhang,
Yonglong Jin,
Haijun Lü
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s243482
Subject(s) - gene knockdown , antisense rna , cancer research , cell growth , survivin , biology , competing endogenous rna , microbiology and biotechnology , carcinogenesis , cell culture , tumor progression , long non coding rna , downregulation and upregulation , gene expression , cancer , gene , biochemistry , genetics
Recent studies suggest many long non-coding RNAs (lncRNAs) are crucial oncogenes or tumor suppressors. This study intended to investigate the biological function and mechanism of lncRNA TTN antisense RNA 1 (TTN-AS1) in the progression of breast cancer (BC).