Open Access<p>Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells</p>
Author(s) -
Lixu Gu,
Qing Li,
Hao Liu,
Xun Lu,
Min Zhu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s240434
Subject(s) - ovarian cancer , paclitaxel , gene knockdown , cancer research , autophagy , microrna , gene silencing , biology , apoptosis , microbiology and biotechnology , chemistry , cancer , biochemistry , gene , genetics
Paclitaxel (PTX) is a first-line chemotherapeutic agent for treating ovarian cancer. However, PTX resistance has become a major obstacle in ovarian cancer therapy. The underlying mechanism associated with PTX resistance is still unclear.