Open Access<p>CircLARP4 Suppresses Cell Proliferation, Invasion and Glycolysis and Promotes Apoptosis in Non-Small Cell Lung Cancer by Targeting miR-135b</p>
Author(s) -
Hua-wei Lu,
Qingwei Guo,
Guozhang Mao,
Junwei Zhu,
Fēi Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s240399
Subject(s) - pten , cancer research , carcinogenesis , protein kinase b , cell growth , apoptosis , downregulation and upregulation , chemistry , microrna , cell , biology , pi3k/akt/mtor pathway , cancer , medicine , biochemistry , gene
CircLARP4 is reported to act as a tumor suppressor in some cancers. However, the detailed roles and molecular basis of circLARP4 in non-small cell lung cancer (NSCLC) tumorigenesis are still unclear. The aim of the study is to explore the potential roles and molecular basis of circLARP4 in NSCLC tumorigenesis.