Open Access
<p>EMP1 Promotes the Proliferation and Invasion of Ovarian Cancer Cells Through Activating the MAPK Pathway</p>
Author(s) -
Yang Liu,
Yiling Ding,
Yanting Nie,
Mengyuan Yang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s240028
Subject(s) - ovarian cancer , metastasis , cancer research , immunohistochemistry , biology , cell growth , epithelial–mesenchymal transition , cancer , medicine , pathology , genetics
Epithelial membrane protein 1 (EMP1), a member of the EMP family, is overexpressed in a large number of tumors and is thought to be a cellular connexin on the cell membrane and is involved in proliferation, invasion, metastasis of tumor cells, and epithelial-mesenchymal transition (EMT). Nevertheless, its biomedical function in ovarian cancer is still unclear.