Open Access<p>Cryptanshinone Inhibits the Glycolysis and Inhibits Cell Migration Through PKM2/β-Catenin Axis in Breast Cancer</p>
Author(s) -
Jiefeng Zhou,
Chih-Ming Su,
Hsin An Chen,
Shicong Du,
Chang Wei Li,
Haoran Wu,
Shin Han Tsai,
YiTing Yeh
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s239134
Subject(s) - pkm2 , clonogenic assay , cancer research , breast cancer , cell migration , cell growth , metastasis , medicine , cancer , cancer cell , cell , chemistry , glycolysis , pyruvate kinase , biochemistry , metabolism
Breast cancer is one of the most prevalent gynecologic malignancies worldwide. Despite the high sensitivity in response to chemotherapy, drug resistance occurred frequently in clinical treatment. Cryptotanshinone (CTS) is a herbal medicine and has been identified as an anti-inflammatory and anti-oxidative drug.