<p>miR-106b-5p Inhibits IRF1/IFN-β Signaling to Promote M2 Macrophage Polarization of Glioblastoma</p>
Author(s) -
Shaojun Yu,
Bin Zhang,
Jian Zhu,
Wu H,
Bin Han,
Qilong Wang,
Qi Chen,
Ming-Hai Wang,
Fang Liu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s238975
Subject(s) - irf1 , glioma , macrophage polarization , gene knockdown , microrna , cancer research , small hairpin rna , downregulation and upregulation , chemistry , macrophage , microbiology and biotechnology , m2 macrophage , biology , cell culture , transcription factor , in vitro , biochemistry , gene , genetics
The microRNA (miRNA) profile changes in the tumor-associated macrophages. However, the role of miR-106b-5p in the glioblastoma-associated macrophages is poorly understood.