Open Access<p>ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer</p>
Author(s) -
Meilin Weng,
Hao Zhang,
Weimin Hou,
Zhirong Sun,
Jing Zhong,
Changhong Miao
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s238973
Subject(s) - gene knockdown , cancer research , colorectal cancer , cell growth , medicine , apoptosis , cell cycle , in vivo , metastasis , cancer , chemistry , biology , biochemistry , microbiology and biotechnology
Colorectal cancer (CRC) is a major disease that threatens human health. It has been reported that the acyl-coenzyme A (CoA): cholesterol acyltransferase 2 ( ACAT2 ) gene can promote the progression of hepatocellular carcinoma, but its function in CRC is still unclear. In this study, we aimed to elucidate the function of ACAT2 in CRC.