Open Access<p>LncRNA TTN-AS1 Promotes Progression of Non-Small Cell Lung Cancer via Regulating miR-491-5p/ZNF503 Axis</p>
Author(s) -
Guanbin Qi,
Lei Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s238890
Subject(s) - gene knockdown , cell growth , cancer research , gene silencing , western blot , lung cancer , viability assay , chemistry , mtt assay , microbiology and biotechnology , competing endogenous rna , cell , epithelial–mesenchymal transition , biology , cell culture , long non coding rna , cancer , medicine , downregulation and upregulation , metastasis , oncology , gene , biochemistry , genetics
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer with high mortality worldwide. Long non-coding RNA (lncRNA) TTN antisense RNA1 (TTN-AS1) has been demonstrated to play a crucial role in a variety of cancers. This study was designed to investigate the function and molecular mechanism of lncRNA TTN-AS1 in NSCLC.