Open Access<p>Eicosapentaenoic acid’s metabolism of 15-LOX-1 promotes the expression of miR-101 thus inhibits Cox2 pathway in colon cancer</p>
Author(s) -
Yi Cai,
Jie Liu,
Shaokang Cai,
Er-Ya Miao,
Cheng-Qian Jia,
YongZhi Fan,
Yingbo Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s237562
Subject(s) - eicosapentaenoic acid , microrna , blot , pathogenesis , function (biology) , colorectal cancer , cancer research , immunofluorescence , immunohistochemistry , real time polymerase chain reaction , chemistry , microbiology and biotechnology , medicine , biology , cancer , biochemistry , immunology , gene , fatty acid , polyunsaturated fatty acid , antibody
It is well known that diet Eicosapentaenoic acid (EPA) is beneficial to colon cancer (CC). However, the underlying molecular mechanisms of EPA-relating miRNAs on genesis and development of this area is still unclear.