Open Access<p>Bioactive Compounds from <em>Abelmoschus manihot L</em>. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment</p>
Author(s) -
Jianhao Hou,
Jinjun Qian,
Zhenlin Li,
Aihua Gong,
Sixia Zhong,
Li Qiao,
Shan Qian,
Yanxin Zhang,
Renjie Dou,
Rui Li,
Ye Yang,
Chunyan Gu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s235944
Subject(s) - flow cytometry , flavonoid , quercetin , kaempferol , manihot , microbiology and biotechnology , bone marrow , medicine , pharmacology , chemistry , biochemistry , biology , immunology , botany , antioxidant
Abelmoschus manihot (L.) Medik. (Malvaceae) derived Huangkui capsules (HKC) represent a traditional Chinese medicine that has been widely applied to the clinical therapy of kidney and inflammatory diseases. The present study aimed to determine the potential therapeutic effects and underlying mechanisms of the ingredients on Multiple Myeloma (MM), an incurable disease that exhibits malignant plasma cell clonal expansion in the bone marrow.