Open Access<p>Progression of Thyroid Carcinoma Is Promoted by the m6A Methyltransferase METTL3 Through Regulating m6A Methylation on TCF1</p>
Author(s) -
Kejin Wang,
Lin Jiang,
Yan Zhang,
Chao Chen
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s234751
Subject(s) - thyroid carcinoma , downregulation and upregulation , cancer research , wnt signaling pathway , methyltransferase , methylation , thyroid cancer , medicine , biology , thyroid , microbiology and biotechnology , gene , signal transduction , genetics
This study aims to uncover the progression of thyroid carcinoma influenced by the m6A methyltransferase METTL3 through regulating m 6 A methylation on TCF1 mRNA and the activated Wnt pathway.