Open Access<p>Long Non-Coding RNA OIP5-AS1 Knockdown Enhances CDDP Sensitivity in Osteosarcoma via miR-377-3p/FOSL2 Axis</p>
Author(s) -
Ling Liu,
Shuya Wang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s232918
Subject(s) - gene knockdown , cisplatin , viability assay , flow cytometry , microbiology and biotechnology , biology , in vivo , apoptosis , antisense rna , rna , cancer research , biochemistry , gene , chemotherapy , genetics
Drug resistance is one of big obstacles for the treatment of tumor. Long non-coding RNA Opa-interacting protein 5-antisense RNA 1 (OIP5-AS1) was identified to involve in drug resistance. In this research, the effects of OIP5-AS1 on cisplatin (CDDP) resistance in osteosarcoma (OS) were mainly investigated.