Open Access<p>Propofol Inhibits the Migration and Invasion of Glioma Cells by Blocking the PI3K/AKT Pathway Through miR-206/ROCK1 Axis</p>
Author(s) -
Dongmei Wang,
Tao Yang,
Junqi Liu,
Yafei Liu,
Na Xing,
Juan He,
Jianjun Yang,
Yanqiu Ai
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s232601
Subject(s) - rock1 , glioma , protein kinase b , pi3k/akt/mtor pathway , chemistry , cancer research , signal transduction , biology , kinase , protein kinase a , biochemistry
Propofol has been identified to perform anti-tumor functions in glioma. However, the molecular mechanisms underlying propofol-induced prevention on migration and invasion of glioma cells remain unclear.