Open Access<p>Elevated Expression of miR-629 Predicts a Poor Prognosis and Promotes Cell Proliferation, Migration, and Invasion of Osteosarcoma</p>
Author(s) -
Xuesen Li,
Na Li,
Qinghui Niu,
HaiBin Zhu,
Zhijie Wang,
Qingxian Hou
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s232479
Subject(s) - oncogene , osteosarcoma , medicine , microrna , biomarker , cancer research , metastasis , cell growth , downregulation and upregulation , real time polymerase chain reaction , oncology , cell , proportional hazards model , clinical significance , log rank test , survival analysis , cancer , cell cycle , biology , gene , biochemistry , genetics
Osteosarcoma (OS) is an invasive bone tumor that primarily affects children and adolescents. MicroRNA-629 (miR-629) acts as an oncogene involved in the development of various cancers. This study aims to reveal the clinical significance and biological function of miR-629 in OS.