Open Access<p>13-[CH2CO-Cys-(Bzl)-OBzl]-Berberine: Exploring The Correlation Of Anti-Tumor Efficacy With ROS And Apoptosis Protein</p>
Author(s) -
Guanyu Li,
Yi Ren,
Xiaoyi Zhang,
Shunying Zhao,
Yaonan Wang,
Jianhui Wu,
Shiqi Peng,
Ming Zhao
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s231035
Subject(s) - xiap , berberine , in vivo , in vitro , chemistry , apoptosis , fluorescein isothiocyanate , mtt assay , western blot , ic50 , isothiocyanate , flow cytometry , cell culture , microbiology and biotechnology , cell growth , pharmacology , biochemistry , caspase , biology , programmed cell death , physics , genetics , quantum mechanics , gene , fluorescence
The discovery of novel derivative of berberine (BBR) having higher anti-tumor activity in vivo is of clinical importance. In this profile, 13-[CH 2 CO-Cys-(Bzl)-OBzl]-berberine (13-Cys-BBR) was prepared for related assays.