Open Access<p>circGFRA1 Enhances NSCLC Progression by Sponging miR-188-3p</p>
Author(s) -
Jie Yao,
Guanxin Xu,
Ling Zhu,
Heqing Zheng
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s230795
Subject(s) - cancer research , pi3k/akt/mtor pathway , protein kinase b , lung cancer , circular rna , rna , microrna , competing endogenous rna , cell growth , long non coding rna , biology , medicine , signal transduction , oncology , gene , microbiology and biotechnology , biochemistry , genetics
Lung cancer continues to be one of the most dangerous tumors around the world. It is an urgency to explore the molecular mechanism of non-small cell lung cancer (NSCLC) progression for developing novel therapeutic approaches. Circular RNA (circRNA) is a novel type of non-coding RNA with a stable closed loop structure. Abnormally expressed circRNAs have been found in many kinds of cancer including NSCLC.