Open Access<p>Long Non-Coding RNA TTN-AS1 Promotes the Proliferation and Invasion of Colorectal Cancer Cells by Activating miR-497-Mediated PI3K/Akt/mTOR Signaling</p>
Author(s) -
Zhenhua Cui,
Bingbing Han,
Xianren Wang,
Zhiwen Li,
Jianxin Wang,
Yanfeng Lv
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s229104
Subject(s) - pi3k/akt/mtor pathway , colorectal cancer , long non coding rna , protein kinase b , cancer research , medicine , signal transduction , microbiology and biotechnology , biology , rna , cancer , gene , genetics
Long non-coding RNAs (lncRNAs) have obtained increasing attention due to their regulatory functions in many cancers. This work aimed to investigate the functional roles of lncRNA TTN-AS1 in colorectal cancer (CRC) and to explore the underlying mechanisms.