Open Access<p>Connexin 43 Modulates the Cellular Resistance to Paclitaxel via Targeting β-Tubulin in Triple-Negative Breast Cancer</p>
Author(s) -
YaoShi Fu,
Xiaoyin Sun,
Zhangyuan Gu,
Zhixiong Zhuang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s229076
Subject(s) - connexin , paclitaxel , gap junction , flow cytometry , cancer research , apoptosis , tubulin , western blot , proximity ligation assay , carcinogenesis , chemistry , immunoprecipitation , triple negative breast cancer , microbiology and biotechnology , cell growth , intracellular , biology , cell culture , microtubule , breast cancer , cancer , gene , biochemistry , genetics , receptor
Triple-negative breast cancer has become an intricate part and hotspot in the clinical and experimental research. Connexins, serving as functional proteins in gap junctions, play an important role in tumorigenesis, cell proliferation and metastasis.