Open Access<p>miR-181a Upregulation Promotes Radioresistance of Nasopharyngeal Carcinoma by Targeting RKIP</p>
Author(s) -
Wei Huang,
Jie Liu,
Shanbiao Hu,
Guangqing Shi,
Yong Zhong,
Jian Li,
Juan Qiu,
Yan Cao,
Yuan Li
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s228800
Subject(s) - radioresistance , nasopharyngeal carcinoma , gene knockdown , in vivo , cancer research , downregulation and upregulation , ectopic expression , microrna , apoptosis , in vitro , transfection , medicine , biology , cell culture , radiation therapy , gene , biochemistry , genetics , microbiology and biotechnology
Radioresistance is the leading cause of treatment failure for nasopharyngeal carcinoma (NPC). Therefore, screening the critical regulators in radioresistance and revealing the underlying mechanisms is imperative for improvement of therapeutical efficacy in NPC.