Open Access<p>Long Noncoding RNA LINC00265 Targets EGFR and Promotes Deterioration of Colorectal Cancer: A Comprehensive Study Based on Data Mining and in vitro Validation</p>
Author(s) -
Hua Ge,
Yan Yan,
Chaosen Yue,
Chaojie Liang,
Jixiang Wu
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s227482
Subject(s) - gene knockdown , colorectal cancer , cancer research , cell cycle , cell growth , carcinogenesis , long non coding rna , apoptosis , downregulation and upregulation , cancer , biology , medicine , gene , genetics
LncRNAs are found to be aberrantly expressed in human cancers and could function as potential oncogenes or tumor suppressor genes. LINC00265 is a newly discovered LncRNA and its function in colorectal cancer (CRC) remains unknown.