Open Access<p>Hypermethylated <em>KLF9</em> Is An Independent Prognostic Factor For Favorable Outcome In Breast Cancer</p>
Author(s) -
Lei Wang,
Qinan Mao,
Shuai Zhou,
Xiuqing Ji
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s226121
Subject(s) - dna methylation , breast cancer , methylation , carcinogenesis , medicine , oncology , cancer research , cancer , malignancy , biomarker , epigenetics , bioinformatics , gene , biology , gene expression , genetics
Breast cancer (BC) is the most lethal human malignancy and is the leading cause of cancer-associated death in women worldwide. Krüppel-like factor 9 ( KLF9 ) belongs to a family of transcriptional regulators and its role in BC has not been fully investigated.