Open Access<p>PD-L1 Expression Is Regulated By NF-κB During EMT Signaling In Gastric Carcinoma</p>
Author(s) -
Dan Xu,
Jing Li,
Ruiyang Li,
Ting Lan,
Chi Xiao,
Ping Gong
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s224053
Subject(s) - epithelial–mesenchymal transition , cancer research , western blot , motility , signal transduction , nf κb , cell migration , chemistry , cell culture , cancer , cell , medicine , biology , microbiology and biotechnology , metastasis , gene , biochemistry , genetics
The aim of this study was to investigate the influence of epithelial-mesenchymal transition (EMT) occurring in gastric carcinoma cells and the involvement of programmed death ligand 1 (PD-L1) expression in tumor cells that undergo EMT. The mechanisms underlying PD-L1 expression during EMT in gastric carcinoma cells were also explored.