Open Access<p>Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway</p>
Author(s) -
Fan Jiang,
Lijun Tian,
Shuhong Huang,
Jing Zhang,
Bin Zhao
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s222895
Subject(s) - protein kinase b , cancer research , hepatocellular carcinoma , flow cytometry , apoptosis , cell growth , oncogene , tumor progression , metastasis , immunohistochemistry , cell culture , medicine , pi3k/akt/mtor pathway , cell migration , transfection , cell , cancer , biology , cell cycle , pathology , immunology , biochemistry , genetics
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. In the present research, we explored a new oncogene, derlin-1 (DERL1), and studied its role and mechanism in human HCC.