Open Access<p>Prognostic Values Of Preoperative Serum CEA And CA125 Levels And Nomograms For Young Breast Cancer Patients</p>
Author(s) -
Xuan Liu,
De-Chang Dai,
Bin Chen,
Sirong He,
Jie Zhang,
Chunjie Wen,
Bin Wang
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s221335
Subject(s) - nomogram , medicine , carcinoembryonic antigen , breast cancer , oncology , multivariate analysis , cancer antigen , receiver operating characteristic , univariate analysis , univariate , cancer , multivariate statistics , statistics , mathematics
Young breast cancer patients have poor prognosis compared to older patients in both overall survival (OS) and loco-regional failure-free survival. Carcinoembryonic antigen (CEA) and Cancer antigen 125 (CA125) have been widely used, but their prognostic value in young breast cancer patients remains unknown. The objectives of this study were to evaluate the prognostic value of preoperative CEA and CA125 serum levels and to build nomograms for better prognostic prediction of young Chinese breast cancer patients using both tumor markers.