Open Access<p>Ganoderan (GDN) Regulates The Growth, Motility And Apoptosis Of Non-Small Cell Lung Cancer Cells Through ERK Signaling Pathway In Vitro And In Vivo</p>
Author(s) -
Weifeng Wang,
Xiaohui Gou,
Xue Hou,
Kai Li
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s221161
Subject(s) - apoptosis , cell growth , a549 cell , blot , cancer research , flow cytometry , vimentin , cell , microbiology and biotechnology , biology , chemistry , immunohistochemistry , immunology , biochemistry , gene
Lung cancer is the most common malignant tumor worldwide. About 90% of lung cancers are considered non-small cell lung cancer (NSCLC). Ganoderan (GDN) is one of the components of Ganoderma lucidum polysaccharides. Ganoderan A (GDNA), Ganoderan B (GDNB) and Ganoderan C (GDNC) were three polysaccharides isolated from the Ganoderma lucidum fruiting body.