Open Access<p>Long Non-Coding RNA TUG1 Modulates Proliferation, Migration, And Invasion Of Acute Myeloid Leukemia Cells Via Regulating miR-370-3p/MAPK1/ERK</p>
Author(s) -
Gang Li,
Peiming Zheng,
Huiling Wang,
Yushu Ai,
Xinjun Mao
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s217795
Subject(s) - myeloid leukemia , gene knockdown , mapk/erk pathway , cancer research , microrna , cell growth , viability assay , carcinogenesis , cell culture , western blot , leukemia , downregulation and upregulation , long non coding rna , microbiology and biotechnology , biology , signal transduction , chemistry , gene , immunology , biochemistry , genetics
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Long non-coding RNA taurine-upregulated gene 1 (lncRNA TUG1) has been discovered to participate in multiple cancers including AML. However, the detailed mechanism of TUG1 in AML remains obscure.