Open Access<p>miR-449a Is Related to Short-Term Recurrence of Hepatocellular Carcinoma and Inhibits Migration and Invasion by Targeting Notch1</p>
Author(s) -
Bing Han,
Jiawei Huang,
Zhenjie Yang,
Jiaqi Zhang,
Xiaomin Wang,
Ning Xu,
Haining Meng,
Junyu Wu,
Qiao Huang,
Xi Yang,
Ruowu Shen,
Changfu Sun
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s216997
Subject(s) - microrna , epithelial–mesenchymal transition , cancer research , hepatocellular carcinoma , metastasis , notch signaling pathway , blot , transfection , cell migration , cell culture , luciferase , signal transduction , biology , chemistry , oncology , medicine , cancer , gene , microbiology and biotechnology , biochemistry , genetics
To explore the effect of miR-449a inhibits migration and invasion by targeting Notch1 and regulating epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC), and further study on the molecular mechanism.