Open Access<p>Knockdown Of Long Non-Coding RNA TP73-AS1 Inhibited Cell Proliferation And Metastasis Through Wnt/β-Catenin Pathway In Lung Adenocarcinoma</p>
Author(s) -
Ying Peng,
Yan Xu,
Guangming Yang,
Shiwei Li,
Zhilian Rui
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s215543
Subject(s) - cancer research , adenocarcinoma , wnt signaling pathway , gene knockdown , long non coding rna , carcinogenesis , gene silencing , metastasis , cell growth , biology , catenin , flow cytometry , apoptosis , signal transduction , microbiology and biotechnology , cancer , downregulation and upregulation , gene , biochemistry , genetics
Various evidences showed that abnormally expressed long non-coding RNAs (lncRNAs) play important roles in the tumorigenesis and progression of malignancies. However, the exact role and regulatory mechanism of lncRNA TP73-AS1 in the pathogenesis and progression of lung adenocarcinoma remain to be further elucidated.