Open Access<p>Silencing stomatin-like protein 2 attenuates tumor progression and inflammatory response through repressing CD14 in liver cancer</p>
Author(s) -
Xiaolin Pu,
Dong Chen,
WenYuan Zhu,
Wei Li,
Hua Jiang
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s215131
Subject(s) - gene silencing , inflammatory response , cancer research , medicine , cd14 , cancer , inflammation , liver cancer , chemistry , gene , biochemistry , receptor
Toll-like receptor 4 (TLR4) is involved in the inflammation in liver cancer. High-expressed stomatin-like protein 2 (SLP-2) is commonly reported in many cancer types. This study aims to investigate the functions of SLP-2 in TLR4-mediated inflammatory responses and tumor progression of liver cancer.