Open Access<p>Embelin Promotes Oncolytic Vaccinia Virus-Mediated Antitumor Immunity Through Disruption of IL-6/STAT3 Signaling in Lymphoma</p>
Author(s) -
Peng Wang,
Yi Wu,
Chen Yang,
Guanan Zhao,
Yonghua Liu,
Gang Cheng,
Shibing Wang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s209312
Subject(s) - oncolytic virus , cancer research , adjuvant , stat3 , vaccinia , immunotherapy , immune system , immunology , medicine , biology , signal transduction , microbiology and biotechnology , recombinant dna , biochemistry , gene
Oncolytic virotherapy is a promising alternative to conventional treatment, yet limited viral replication and immune-negative feedback are the major hurdles to effective viro-immunotherapy.