Open Access<p>t(15; 17) associated with primary myelofibrosis: a case report of an unusual clinical presentation and diagnostic dilemma</p>
Author(s) -
Kalyan Nadiminti,
Margarida Silverman,
Sharathkumar Bhagavathi,
Praveen Vikas
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s208290
Subject(s) - myelofibrosis , myeloproliferative neoplasm , medicine , acute promyelocytic leukemia , ruxolitinib , bone marrow , biopsy , pathology , cancer research , retinoic acid , biology , gene , biochemistry
primary myelofibrosis (PMF) is a myeloproliferative neoplasm which is associated with clonal molecular and cytogenetic abnormalities (CA) and varied clinical manifestations. While various CA have been previously described, t(15; 17) has not been reported in association with this condition.