Open Access<p>In vitro mitochondrial-targeted antioxidant peptide induces apoptosis in cancer cells</p>
Author(s) -
Wei Zhan,
Xin Liao,
Lianghe Li,
Zhongsheng Chen,
Tian Tian,
Lei Yu,
Zupeng Chen
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s207640
Subject(s) - reactive oxygen species , hela , mitochondrion , apoptosis , mitochondrial ros , cancer cell , oxidative stress , chemistry , microbiology and biotechnology , biochemistry , cell , biology , cancer , genetics
Reactive oxygen species (ROS) are major contributors to cancer and involved in numerous tumor proliferation signaling pathways. Mitochondria are the major ROS-producing organelles, and ROS are produced from the synthesis of adenosine triphosphate and cell metabolism.