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Multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene, is involved in the efflux of certain anticancer drugs. Here we observed whether the ABCC2 (G1249A) polymorphism impacts the transport abilities of MRP2-dependent paclitaxel, docetaxel, and doxorubicin in recombinant LLC-PK1 cell lines.

<p>In vitro Transport Ability of <em>ABCC2</em> (G1249A) Polymorphic Variant Towards Anticancer Drugs</p>