Open Access<p>Multiple myeloma with dural mater involvement</p>
Author(s) -
Su Liu,
Xubin Li,
Yueyang Li,
Dongying Li,
Yafei Wang,
Chen Tian
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s202662
Subject(s) - medicine , dura mater , multiple myeloma , lenalidomide , malignancy , pathology , infiltration (hvac) , surgery , physics , thermodynamics
Multiple myeloma is an incurable clonal B-cell malignancy which may present with neoplastic monoclonal plasma cells in either bone or soft tissues. Central nervous system (CNS) involvement such as dural myeloma or intraparenchymal infiltration, or with diffuse leptomeningeal involvement, is uncommon. Dural involvement of myeloma without parenchymal or leptomeningeal disease is an even rarer occurrence; therefore there are no established treatment guidelines for CNS myelomatosis. Here we reported a refractory MM patient progressed to dura mater involvement after the induction therapy but showed good response to lenalidomide treatment.