Open Access<p>LncRNA PVT1 promotes proliferation, invasion and epithelial–mesenchymal transition of renal cell carcinoma cells through downregulation of miR-16-5p</p>
Author(s) -
Yu Ren,
Weijian Huang,
Guobin Weng,
Pinger Cui,
Haote Liang,
Yeping Li
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s190239
Subject(s) - pvt1 , cancer research , downregulation and upregulation , gene silencing , oncogene , viability assay , cell , apoptosis , transfection , biology , cell growth , cell culture , chemistry , microbiology and biotechnology , cell cycle , long non coding rna , gene , biochemistry , genetics
LncRNAs have recently emerged as vital regulators in the pathogenesis and development of various cancers. LncRNA PVT1 is reported to function as an oncogene in some tumors. However, the role of PVT1 in RCC remains unknown.