Open AccessThe effect of allicin on cell proliferation and apoptosis compared to blank control and cis-platinum in oral tongue squamous cell carcinoma
Author(s) -
Yanjun Guo,
Hongli Liu,
Yong Chen,
Yan Wei
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s178718
Subject(s) - allicin , apoptosis , chemistry , cell growth , annexin , propidium iodide , cell , microbiology and biotechnology , cisplatin , western blot , biochemistry , programmed cell death , biology , medicine , chemotherapy , gene
Oral tongue squamous cell carcinoma (OTSCC) has aggressive clinical behavior with poor prognosis. Allicin plays a tumor-suppressive role in various cancers, although the role of allicin in OTSCC is unknown. We aimed to investigate the effect of allicin on cell proliferation and apoptosis compared to blank control and cis-platinum in OTSCC.