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Non-small-cell lung cancer (NSCLC) constitutes the leading cause of cancer death in humans. Previous studies revealed the essential role of the protein arginine methyltransferase 7 ( PRMT7 ) in promoting metastasis in breast cancer. However, its function and potential mechanism in NSCLC remain unclear.

oncotargets and therapy

&lt;em&gt;PRMT7&lt;/em&gt; contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with &lt;em&gt;HSPA5&lt;/em&gt; and &lt;em&gt;EEF2&lt;/em&gt;