Open Access<em>PRMT7</em> contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with <em>HSPA5</em> and <em>EEF2</em>
Author(s) -
Dapeng Cheng,
Zhifeng He,
Liangcheng Zheng,
Deyao Xie,
Suyu Dong,
Peng Zhang
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s166412
Subject(s) - carcinogenesis , cancer research , metastasis , lung cancer , biology , kegg , matrigel , gene , cancer , gene expression , genetics , medicine , pathology , gene ontology , angiogenesis
Non-small-cell lung cancer (NSCLC) constitutes the leading cause of cancer death in humans. Previous studies revealed the essential role of the protein arginine methyltransferase 7 ( PRMT7 ) in promoting metastasis in breast cancer. However, its function and potential mechanism in NSCLC remain unclear.