Open AccessUpregulation of circulating miR130a is correlated with development of Barrett’s esophagus and esophageal adenocarcinoma
Author(s) -
Li Wang,
Feng Ji,
Gang Liu,
Wei Wang,
Zhitong Li,
Yongqiang Yue,
Zhonggao Wang
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s162603
Subject(s) - medicine , downregulation and upregulation , malignancy , beijing , esophagus , adenocarcinoma , china , gastroenterology , general surgery , cancer , biochemistry , gene , chemistry , political science , law
Barrett's esophagus (BE) is one of the major known risk factors for esophageal adenocarcinoma (EAC). Circulating miRNAs are emerging as predictive biomarkers for early detection of malignancy. However, the potential for circulating miRNAs to be used as biomarkers for BE neoplastic progression to EAC has not been well characterized.