Open AccessBiological Therapy in Noninfectious Pediatric Uveitis: A Systematic Review
Author(s) -
Luiz Fernando Norcia,
Olívia Pereira Kiappe,
Eliane Chaves Jorge
Publication year - 2021
Publication title -
clinical ophthalmology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 56
eISSN - 1177-5483
pISSN - 1177-5467
DOI - 10.2147/opth.s322445
Subject(s) - medicine , adalimumab , adverse effect , infliximab , uveitis , placebo , relative risk , confidence interval , blinding , meta analysis , randomized controlled trial , disease , ophthalmology , pathology , alternative medicine
Noninfectious pediatric uveitis is a potentially blinding disease often associated with systemic conditions. In cases of chronic anterior uveitis without adequate response to steroids and immunosuppressants, biological response modifiers would be viable therapeutic options. Still, evidence is lacking on the safety of the long-term use of these drugs in children. Therefore, this study aimed to evaluate the efficacy and safety of biological therapy to treat noninfectious pediatric uveitis.