Open Access<p>Giant Cell Arteritis: The Experience of Two Collaborative Referral Centers and an Overview of Disease Pathogenesis and Therapeutic Advancements</p>
Author(s) -
Rosanna Dammacco,
Giovanni Alessio,
Ermete Giancipoli,
Patrizia Leone,
Anna Cirulli,
Leonardo Resta,
Franco Dammacco
Publication year - 2020
Publication title -
clinical ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 56
eISSN - 1177-5483
pISSN - 1177-5467
DOI - 10.2147/opth.s243203
Subject(s) - medicine , giant cell arteritis , polymyalgia rheumatica , retrospective cohort study , vasculitis , central retinal artery occlusion , constitutional symptoms , cohort , arteritis , surgery , ophthalmology , visual acuity , disease
Giant cell arteritis (GCA), a chronic vasculitis of the large and medium-sized arteries, affects people >50 years of age. This study assessed the prevalence of visual manifestations and other clinical features at presentation in an Italian cohort of GCA patients. Recent advances in the pathophysiology, diagnosis, and therapy of GCA are also reviewed.